Electrical and Computer Engineering 795:
Quantitative Electrophysiology
(Fall 2014)


To provide a solid quantitative understanding of the behaviour of excitable cells, the resulting extracellular fields, measurement of extracellular fields using techniques such as EMG and EEG, and functional electrical stimulation of excitable cells for neural and muscular prostheses.


Dr. Hubert de Bruin,
ITB-A211, ext. 24171.

Dr. Ian Bruce,
ITB-A213, ext. 26984.



A basic undergraduate understanding of electrostatics, electrical circuits, linear systems, and ordinary & partial differential equations.

Course Outline: (subject to change)

  1. Introduction to excitable cells; Equivalent electrical circuits for cell membranes
  2. Cell excitability; Introduction to the Hodgkin-Huxley model
  3. Linear cable equations; Propagation of electrical potential waveforms
  4. Chemical synapses and gap junctions; Dendritic trees
  5. Muscle physiology
  6. Models for generation of extracellular fields
  7. Measurement of bioelectric potentials (electrodes, differential amplification, filtering, data acquisition, etc.)
  8. Electromyography (EMG)
  9. Electroencephalography (EEG)
  10. Fundamentals of functional electrical stimulation (FES)
  11. Electrodes and sources for FES; Applications of FES


Assignment (15%); Project (25%); Midterm Exam (20%); Final Exam (40%).




There will be one 3-hour lecture per week over eleven weeks, at 1:30–4:30pm on Wednesdays in ETB-534 (starting Sept. 10th).

Slides for:

Lecture #1 (Wednesday, September 10); Lecture #2 (Wednesday, September 17)
Lecture #3 (Wednesday, September 24); Lecture #4 (Wednesday, October 1)
Lecture #5 (Wednesday, October 8); Lecture #6 (Wednesday, October 15)
Lecture #7 (Wednesday, October 22); Lecture #8 (Wednesday, October 29)
Lecture #9 (Wednesday, November 5); Lecture #10 (Wednesday, November 19)
Lecture #11 (Wednesday, November 26)

Midterm Exam:


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Last updated Wedneday, November 26, 2014