Medical Imaging Engineering & Physics

Dr. Michael D. NoseworthyPhD, P.Eng. · Professor, McMaster University

I develop MRI and in vivo NMR spectroscopy methods to measure tissue microstructure and metabolism — and apply them to understand injury, disease and recovery in the brain, muscle and body.

Portrait of Dr. Michael Noseworthy
190+peer-reviewed journal articles
2003at McMaster & St. Joseph’s since
MRI + MRS¹H, ³¹P and ²³Na methods
P.Eng.Professional Engineers Ontario

About

Imaging how tissue is built — and how it works

Dr. Michael Noseworthy is a Professor in the Department of Electrical and Computer Engineering at McMaster University and Director of Imaging Physics and Engineering at the Imaging Research Centre (IRC) of St. Joseph’s Healthcare Hamilton and at the Centre for Integrated and Advanced Medical Imaging (CIAMI). He is also Associate Chair (Research) in the Department of Medical Imaging and holds Special Professional Staff appointments in Radiology and Nuclear Medicine.

His research assesses normal and diseased tissue microstructure and how changes in that structure affect tissue metabolism. His group builds new MRI hardware, imaging pulse sequences and signal- and image-processing software, and applies them to physiological questions and disease. More recently the work has expanded to multimodal approaches that combine MRI with EEG, EMG and ultrasound, along with complex-systems mathematics and machine learning for image analysis.

He trained at the University of Guelph (BSc, MSc, PhD), held a postdoctoral fellowship in imaging physics at Sunnybrook (University of Toronto, Medical Biophysics), and was a Scientist and MRI Physicist at The Hospital for Sick Children and an Assistant Professor at the University of Toronto before joining St. Joseph’s and McMaster in 2003. From 2010 to 2020 he served as Co-Director of the McMaster School of Biomedical Engineering.

Research

Research themes

From RF coils and pulse sequences to clinical studies — engineering the measurement, then using it to answer physiological questions.

Tissue microstructure & metabolism

Diffusion MRI and multinuclear in vivo spectroscopy to quantify how tissue is organized and how it uses energy.

Diffusion tensor imaging³¹P MRS²³Na MRIGABA MRS

Brain injury & neuroimaging

Resting-state fMRI, DTI and spectroscopy to understand concussion and recovery — including the effects of exercise in youth.

Pediatric concussionrs-fMRINormative modellingAging

Muscle, fat & metabolic health

Imaging skeletal muscle function, brown adipose tissue and organ fat to study exercise, obesity, diabetes and musculoskeletal disease.

Muscle BOLD & DTIBrown fatLiver fatKnee OA

MRI engineering & fast imaging

RF coils, pulse sequences, compressed sensing and quality-control phantoms — including hyperpolarized ¹²⁹Xe lung MRI and 7 T methods.

RF hardwareCompressed sensing¹²⁹Xe lung MRIQC phantoms

Multimodal imaging & AI

Fusing MRI with EEG, EMG and ultrasound, and using fractal/complex-systems analysis and machine learning to extract new biomarkers.

Simultaneous MRI–EMGEEG–fMRIMachine learningFractal analysis

People

Lab members

The trainees and staff behind our research, and the projects they are working on.

Publications

Publications

Peer-reviewed journal articles. Newly published papers are added automatically from my ORCID record. For citation metrics, see my Google Scholar profile.

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News

Latest from LinkedIn

Announcements, papers, talks and lab news.

On the road

Recent conferences

Talks, posters and moments from meetings our group has attended. Select a conference to see its photos.

Teaching

Courses

BIOMED 702 /
ECE 780 /
MED PHYS 702
Magnetic Resonance and Ultrasound Imaging
Formerly called Medical Imaging Systems II
Graduate · Fall 2026
ELEC ENG 4BF4
Advanced Medical Imaging
Undergraduate · Winter 2026
IBEHS 4D03
Introduction to Medical Imaging
Undergraduate · Winter 2026

Career

Background

  1. 2022 – present
    Associate Chair (Research)
    Department of Medical Imaging, McMaster University
  2. 2016 – present
    Professor
    Electrical & Computer Engineering, McMaster University (Associate Professor 2010–2016; Assistant Professor 2007–2010)
  3. 2010 – 2020
    Co-Director
    McMaster School of Biomedical Engineering
  4. 2003 – present
    Director of Imaging Physics & Engineering, Imaging Research Centre (IRC) and CIAMI; Affiliate Scientist, FSORC. Assistant Professor, Radiology, McMaster (2003–2007)
  5. 2000 – 2003
    Scientist & MRI Physicist
    The Hospital for Sick Children and University Health Network; Assistant Professor, University of Toronto
  6. 1996 – 1999
    Postdoctoral Fellow, Imaging Physics
    Sunnybrook Health Sciences Centre, Medical Biophysics, University of Toronto
  7. 1983 – 1997
    PhD (1997), MSc (1992), BSc (1987)
    University of Guelph — Applied Physics / Medical Imaging (PhD); Biomedical Sciences / Medical Imaging (MSc)
President’s Award for Excellence in Graduate SupervisionMcMaster University, 2013
Distinguished Fellow Adjunct ProfessorMohawk College, 2024
Professional membershipsProfessional Engineers Ontario (P.Eng.) · ISMRM · ESMRMB · Canadian Traumatic Brain Injury Research Consortium (CTRC)

Contact

Get in touch

Email & phone

nosewor@mcmaster.ca
905-525-9140 ext. 23727

Office

Imaging Research Centre
Fontbonne Building, Room 130A
St. Joseph’s Healthcare Hamilton

Mailing address

Dept. of Electrical & Computer Engineering
McMaster University, 1280 Main Street West
Hamilton, ON L8S 4L7, Canada

Profiles